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Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of -ketoglutarate-dependent dioxygenases
Other remedies for treating depression, which can also help manage weight, include: undergoing counseling exercising, such as walking at least 30 minuteseach day following a varied, nutritious diet and eating regular meals establishing or maintaining a regular sleep pattern connecting with others avoiding the use of alcohol, nicotine, and drugs that a doctor has not recommended If these remedies do not help with mood or weight, a person can ask a doctor for more support
Omega-3 fatty acids can competitively inhibit AA metabolism, and compete with AA to bind COX-2 and LOX enzymes through EPA, reducing the production of pro-inflammatory mediators' prostaglandin E2 and leukotriene B4 (72)
